Zetigo™ PRM fungicide: Delivering a new active ingredient for anthracnose control in lentils

decorative image
Something went wrong. Please try again later...

Like all pulse diseases, anthracnose is learning to adapt. And quickly, too. Anthracnose is the most prominent disease in lentils, and it has been primarily treated, successfully, with strobilurin fungicides (Group 11).

But in 2019, researchers in Saskatchewan found high levels of anthracnose that was insensitive to all strobilurin products, making control that much more complicated. In 2020, a survey of lentil fields in Saskatchewan confirmed that strains of anthracnose that are insensitive (or resistant) to Group 11 fungicides are more abundant than strains that can be controlled by strobilurins.1

Integrated disease management practices are key, but farmers are also looking for new fungicide tools to help them get back on top of anthracnose and protect their valuable crop. Now they have one in Zetigo™ PRM fungicide with Adavelt™ active from Corteva Agriscience™. Here’s what you should know.

A novel mode of action in the fungicide category

Adavelt active (florylpioxamid) is a Group 21 fungicide that provides an entirely new mode of action (MoA) against many pulse diseases, including Group 11 insensitive anthracnose. It was derived from a naturally occurring fungicide found in soil microbes and it controls a wide range of Ascomycetes pathogens, including Septoria, Botrytis, Alternaria and more. Plus, Adavelt active has no cross-resistance to other modes of action, making it a powerful new resistance management tool.

How it works

All fungicide active ingredients work by binding to a specific site within a fungal pathogen and shutting it down. All Group 7 fungicides, for example, are known as succinate dehydrogenase inhibitors (SHDIs) because they bind to and inhibit a specific point in the succinate dehydrogenase (SDH) complex. Group 11 strobilurins bind to what’s known as the Qo or Quinone “outside” site. Adavelt active (Group 21) binds to a different site altogether – Qi – offering a new mode of action against fungal pathogens.

Specifically, Adavelt active stops the growth of fungal mycelia, stopping the spread of disease within a plant. It also stops spores from germinating on leaf surfaces and reduces the development of viable pycnidiospores, which can spread to nearby plants. It is mainly a preventative fungicide with translaminar activity for uniform protection throughout treated plant tissue.

Zetigo PRM fungicide in Canada

Zetigo PRM with Adavelt active is a pre-mix of florylpioxamid (Group 21) and pyraclostrobin (Group 11) and was approved in Canada in 2023 for control of anthracnose in lentils. A full product launch with an expanded label is planned for 2024.

Corteva scientists designed Zetigo PRM thoughtfully with an eye to achieving the highest possible efficiency with the lowest possible rate of Adavelt active, and they succeeded. Adavelt active offers excellent crop safety, high efficacy, and a low environmental load. The addition of pyraclostrobin increases plant health and adds a second mode of action for elevated disease control and resistance management now, while prolonging the potential risk of resistance to Adavelt active. 

Beyond anthracnose

Pulse diseases tend to develop insensitivity (resistance) to fungicide active ingredients quicker than the diseases of other major crops. It means pulse growers are always in a cat and mouse game of seeing who can thwart who first. The need for a new, effective mode of action against pulse disease was paramount and Zetigo PRM with Adavelt active has arrived at just the right time.

While it’s not only for lentil growers facing challenging anthracnose incidence – the potential for Adavelt active in other pulse crops against other diseases is huge. As the first broad-spectrum picolinamide fungicide for use against Ascomycetes pathogens in over 30 crops, Corteva expects to add new pulse crops (along with new diseases controlled) to the label in time for the 2024 growing season.

It means pulse growers at last have a new tool to not only defend their crops against many yield-and quality-robbing diseases but can also get a leg up when it comes to managing fungicide resistance in pulses.

1Saskatchewan Pulse Growers: Anthracnose in Lentils: Managing Fungicide Insensitivity, April 2023. https://saskpulse.com/resources/anthracnose-in-lentils-managing-fungicide-insensitivity/#:~:text=Recently%2C%20high%20levels%20of%20insensitivity,to%20all%20Group%2011%20fungicides.